ea0015p109 | Cytokines and growth factors | SFEBES2008
Banerjee Moulinath
, Austin Clare
, Vyas Avni
, Siddals Kirk
, Gibson Martin
, Malik Rayaz
, Cruickshank Kennedy
Introduction: IGF-I and its binding proteins may modulate cardiovascular risk. As part of our Manchester MothersÂ’ Cardiovascular study, we tested in pre-menopausal women the hypothesis that higher circulating IGF-I concentrations would be associated with lesser arterial stiffness and lower cardiac (LV) mass, while higher IGFBP1, reflecting less pre-hepatic insulin, would be positively related to small vessel function.Methods: About 193 women aged 32...